F91S (p.Phe91Ser) variant of CD40LG (CD40 ligand)
F91S (p.Phe91Ser) in CD40LG (CD40 ligand) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data, published literature, and structural context.
F91S (p.Phe91Ser) variant details
- p.Phe91Ser
- gnomAD X-136650381-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.534
- REVEL 0.62
- MetaLR 0.37
- MetaSVM -0.24
- CADD 26.10
- PolyPhen-2 0.92
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available