F65L (p.Phe65Leu) variant of CD40LG (CD40 ligand)
F65L (p.Phe65Leu) in CD40LG (CD40 ligand) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data, published literature, and structural context.
F65L (p.Phe65Leu) variant details
- p.Phe65Leu
- gnomAD X-136650304-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.424
- REVEL 0.49
- MetaLR 0.43
- MetaSVM -0.11
- CADD 24.90
- PolyPhen-2 0.92
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available