E85G (p.Glu85Gly) variant of CD40LG (CD40 ligand)
E85G (p.Glu85Gly) in CD40LG (CD40 ligand) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, published literature, and structural context.
E85G (p.Glu85Gly) variant details
- p.Glu85Gly
- gnomAD X-136650363-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.351
- REVEL 0.31
- MetaLR 0.27
- MetaSVM -0.66
- CADD 25.00
- PolyPhen-2 0.51
- SIFT 0.07
- Population evidence available
- Structural context available
- Literature evidence available