W11S (p.Trp11Ser) variant of CD40 (P25942)
W11S (p.Trp11Ser) in CD40 (P25942) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data, published literature, and structural context.
W11S (p.Trp11Ser) variant details
- p.Trp11Ser
- gnomAD 20-46118375-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.595
- REVEL 0.64
- CADD 31.00
- PolyPhen-2 0.84
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 5.4e-06)
- Structural context available
- Literature evidence available