T24S (p.Thr24Ser) variant of CD40 (P25942)
T24S (p.Thr24Ser) in CD40 (P25942) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
T24S (p.Thr24Ser) variant details
- p.Thr24Ser
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.137
- REVEL 0.13
- CADD 11.40
- PolyPhen-2 0.04
- SIFT 0.12
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available