T24I (p.Thr24Ile) variant of CD40 (P25942)
T24I (p.Thr24Ile) in CD40 (P25942) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data, published literature, and structural context.
T24I (p.Thr24Ile) variant details
- p.Thr24Ile
- gnomAD 20-46121839-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.177
- REVEL 0.18
- CADD 14.80
- PolyPhen-2 0.00
- SIFT 0.40
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available