S39P (p.Ser39Pro) variant of CD40 (P25942)
S39P (p.Ser39Pro) in CD40 (P25942) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
S39P (p.Ser39Pro) variant details
- p.Ser39Pro
- ExAC rs766167612
- TOPMed rs766167612
- gnomAD rs766167612
- Missense
- Variant Prioritization Score for Impact Estimate 0.312
- REVEL 0.42
- CADD 14.00
- PolyPhen-2 0.10
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available