S35T (p.Ser35Thr) variant of CD40 (P25942)
S35T (p.Ser35Thr) in CD40 (P25942) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, published literature, and structural context.
S35T (p.Ser35Thr) variant details
- p.Ser35Thr
- gnomAD 20-46121872-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.137
- REVEL 0.06
- MetaLR 0.25
- MetaSVM -0.80
- CADD 14.30
- PolyPhen-2 0.07
- SIFT 0.11
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available