S35C (p.Ser35Cys) variant of CD40 (P25942)
S35C (p.Ser35Cys) in CD40 (P25942) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
S35C (p.Ser35Cys) variant details
- p.Ser35Cys
- ExAC rs750234130
- gnomAD rs750234130
- Missense
- Variant Prioritization Score for Impact Estimate 0.272
- REVEL 0.30
- CADD 21.10
- PolyPhen-2 0.73
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available