R90G (p.Arg90Gly) variant of CD40 (P25942)
R90G (p.Arg90Gly) in CD40 (P25942) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data, published literature, and structural context.
R90G (p.Arg90Gly) variant details
- p.Arg90Gly
- gnomAD 20-46122621-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.382
- REVEL 0.43
- MetaLR 0.43
- MetaSVM -0.64
- CADD 13.90
- PolyPhen-2 0.09
- SIFT 0.42
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available