R3P (p.Arg3Pro) variant of CD40 (P25942)
R3P (p.Arg3Pro) in CD40 (P25942) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
R3P (p.Arg3Pro) variant details
- p.Arg3Pro
- TOPMed rs1309660087
- gnomAD rs1309660087
- Missense
- Variant Prioritization Score for Impact Estimate 0.194
- REVEL 0.17
- CADD 17.20
- PolyPhen-2 0.01
- SIFT 0.10
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available