R3L (p.Arg3Leu) variant of CD40 (P25942)
R3L (p.Arg3Leu) in CD40 (P25942) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
R3L (p.Arg3Leu) variant details
- p.Arg3Leu
- TOPMed rs1309660087
- gnomAD rs1309660087
- Missense
- Variant Prioritization Score for Impact Estimate 0.171
- REVEL 0.14
- CADD 15.70
- PolyPhen-2 0.01
- SIFT 0.16
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available