P85T (p.Pro85Thr) variant of CD40 (P25942)
P85T (p.Pro85Thr) in CD40 (P25942) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
P85T (p.Pro85Thr) variant details
- p.Pro85Thr
- ExAC rs769971386
- gnomAD rs769971386
- Missense
- Variant Prioritization Score for Impact Estimate 0.302
- REVEL 0.30
- CADD 21.20
- PolyPhen-2 0.32
- SIFT 0.05
- Most common in the South Asian population (allele frequency 3.5e-05)
- Structural context available