N86Y (p.Asn86Tyr) variant of CD40 (P25942)
N86Y (p.Asn86Tyr) in CD40 (P25942) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data, published literature, and structural context.
N86Y (p.Asn86Tyr) variant details
- p.Asn86Tyr
- gnomAD 20-46122358-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.451
- REVEL 0.50
- MetaLR 0.64
- MetaSVM 0.32
- CADD 23.20
- PolyPhen-2 0.18
- SIFT 0.02
- Population evidence available
- Structural context available
- Literature evidence available