L60V (p.Leu60Val) variant of CD40 (P25942)
L60V (p.Leu60Val) in CD40 (P25942) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data, published literature, and structural context.
L60V (p.Leu60Val) variant details
- p.Leu60Val
- gnomAD 20-46122280-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.124
- REVEL 0.12
- MetaLR 0.13
- MetaSVM -1.03
- CADD 0.00
- PolyPhen-2 0.00
- SIFT 0.75
- Population evidence available
- Structural context available
- Literature evidence available