L60F (p.Leu60Phe) variant of CD40 (P25942)
L60F (p.Leu60Phe) in CD40 (P25942) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data, published literature, and structural context.
L60F (p.Leu60Phe) variant details
- p.Leu60Phe
- gnomAD 20-46122280-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.149
- REVEL 0.16
- MetaLR 0.19
- MetaSVM -0.75
- CADD 0.00
- PolyPhen-2 0.09
- SIFT 0.62
- Population evidence available
- Structural context available
- Literature evidence available