L32P (p.Leu32Pro) variant of CD40 (P25942)
L32P (p.Leu32Pro) in CD40 (P25942) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
L32P (p.Leu32Pro) variant details
- p.Leu32Pro
- ExAC rs764464873
- gnomAD rs764464873
- Missense
- Variant Prioritization Score for Impact Estimate 0.313
- REVEL 0.45
- CADD 9.58
- PolyPhen-2 0.03
- SIFT 0.23
- Most common in the South Asian population (allele frequency 0.00016)
- Structural context available