I33T (p.Ile33Thr) variant of CD40 (P25942)
I33T (p.Ile33Thr) in CD40 (P25942) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
I33T (p.Ile33Thr) variant details
- p.Ile33Thr
- TOPMed rs1404215817
- gnomAD rs1404215817
- Missense
- Variant Prioritization Score for Impact Estimate 0.193
- REVEL 0.28
- CADD 1.25
- PolyPhen-2 0.01
- SIFT 0.39
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available