H80R (p.His80Arg) variant of CD40 (P25942)
H80R (p.His80Arg) in CD40 (P25942) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.56 / 1. The record also includes population frequency data and structural context.
H80R (p.His80Arg) variant details
- p.His80Arg
- ESP rs376829285
- TOPMed rs376829285
- gnomAD rs376829285
- Missense
- Variant Prioritization Score for Impact Estimate 0.561
- REVEL 0.52
- CADD 23.30
- PolyPhen-2 0.83
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available