G88R (p.Gly88Arg) variant of CD40 (P25942)
G88R (p.Gly88Arg) in CD40 (P25942) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data, published literature, and structural context.
G88R (p.Gly88Arg) variant details
- p.Gly88Arg
- gnomAD 20-46122615-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.436
- REVEL 0.34
- MetaLR 0.68
- MetaSVM -0.30
- CADD 23.90
- PolyPhen-2 0.99
- SIFT 0.02
- Population evidence available
- Structural context available
- Literature evidence available