D84N (p.Asp84Asn) variant of CD40 (P25942)
D84N (p.Asp84Asn) in CD40 (P25942) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
D84N (p.Asp84Asn) variant details
- p.Asp84Asn
- rs1406703700
- TOPMed rs1406703700
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.32
- REVEL 0.25
- CADD 22.90
- PolyPhen-2 0.06
- SIFT 0.05
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the South Asian population (allele frequency 3.5e-05)
- Structural context available