D84E (p.Asp84Glu) variant of CD40 (P25942)
D84E (p.Asp84Glu) in CD40 (P25942) is a missense change. Clinical records from EBI and UniProt describe it as likely benign. The record also includes variant effect predictions and structural context.
D84E (p.Asp84Glu) variant details
- p.Asp84Glu
- ExAC rs748382649
- TOPMed rs748382649
- gnomAD rs748382649
- Likely benign
- Missense
- MetaLR 0.32
- MetaSVM -0.80
- SIFT 0.67
- EBI: Likely benign
- UniProt: Likely benign
- Structural context available