C26G (p.Cys26Gly) variant of CD40 (P25942)
C26G (p.Cys26Gly) in CD40 (P25942) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.76 / 1. The record also includes population frequency data, published literature, and structural context.
C26G (p.Cys26Gly) variant details
- p.Cys26Gly
- gnomAD 20-46121844-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.758
- REVEL 0.83
- CADD 28.40
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available