S16T (p.Ser16Thr) variant of CD3E (P07766)
S16T (p.Ser16Thr) in CD3E (P07766) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
S16T (p.Ser16Thr) variant details
- p.Ser16Thr
- gnomAD rs1233910437
- Missense
- Variant Prioritization Score for Impact Estimate 0.146
- REVEL 0.11
- MetaLR 0.15
- MetaSVM -0.83
- CADD 8.64
- PolyPhen-2 0.40
- SIFT 0.57
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available