L58P (p.Leu58Pro) variant of CD3E (P07766)
L58P (p.Leu58Pro) in CD3E (P07766) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
L58P (p.Leu58Pro) variant details
- p.Leu58Pro
- ExAC rs767092797
- TOPMed rs767092797
- gnomAD rs767092797
- Missense
- Variant Prioritization Score for Impact Estimate 0.0965
- REVEL 0.08
- MetaLR 0.07
- MetaSVM -1.03
- CADD 0.22
- PolyPhen-2 0.04
- SIFT 0.17
- Most common in the HGDP:FRENCH population (allele frequency 0.019)
- Structural context available