L15F (p.Leu15Phe) variant of CD3E (P07766)
L15F (p.Leu15Phe) in CD3E (P07766) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
L15F (p.Leu15Phe) variant details
- p.Leu15Phe
- Ensembl rs1948097990
- Missense
- Variant Prioritization Score for Impact Estimate 0.236
- REVEL 0.22
- MetaLR 0.28
- MetaSVM -0.76
- CADD 19.10
- PolyPhen-2 0.98
- SIFT 0.16
- Most common in the 1KG:CLM population (allele frequency 0.0053)
- Structural context available