L14V (p.Leu14Val) variant of CD3E (P07766)
L14V (p.Leu14Val) in CD3E (P07766) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data, published literature, and structural context.
L14V (p.Leu14Val) variant details
- p.Leu14Val
- gnomAD 11-118304992-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.322
- REVEL 0.24
- MetaLR 0.29
- MetaSVM -0.33
- CADD 23.60
- PolyPhen-2 0.83
- SIFT 0.05
- Population evidence available
- Structural context available
- Literature evidence available