I75V (p.Ile75Val) variant of CD3E (P07766)
I75V (p.Ile75Val) in CD3E (P07766) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data and structural context.
I75V (p.Ile75Val) variant details
- p.Ile75Val
- TOPMed rs1948142768
- Missense
- Variant Prioritization Score for Impact Estimate 0.0658
- REVEL 0.03
- MetaLR 0.02
- MetaSVM -1.01
- CADD 0.10
- PolyPhen-2 0.03
- SIFT 0.27
- Most common in the Middle Eastern population (allele frequency 0.0007)
- Structural context available