I75T (p.Ile75Thr) variant of CD3E (P07766)
I75T (p.Ile75Thr) in CD3E (P07766) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data, published literature, and structural context.
I75T (p.Ile75Thr) variant details
- p.Ile75Thr
- gnomAD 11-118312738-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.108
- REVEL 0.10
- MetaLR 0.03
- MetaSVM -1.02
- CADD 0.94
- PolyPhen-2 0.15
- SIFT 0.13
- Most common in the Non-Finnish European population (allele frequency 8.8e-05)
- Structural context available
- Literature evidence available