I66V (p.Ile66Val) variant of CD3E (P07766)
I66V (p.Ile66Val) in CD3E (P07766) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
I66V (p.Ile66Val) variant details
- p.Ile66Val
- ExAC rs763670617
- gnomAD rs763670617
- Missense
- Variant Prioritization Score for Impact Estimate 0.083
- REVEL 0.03
- MetaLR 0.04
- MetaSVM -1.10
- CADD 0.00
- PolyPhen-2 0.00
- SIFT 0.45
- Most common in the HGDP:MAKRANI population (allele frequency 0.023)
- Structural context available