I66T (p.Ile66Thr) variant of CD3E (P07766)
I66T (p.Ile66Thr) in CD3E (P07766) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data, published literature, and structural context.
I66T (p.Ile66Thr) variant details
- p.Ile66Thr
- gnomAD 11-118312711-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.0803
- REVEL 0.01
- MetaLR 0.06
- MetaSVM -1.05
- CADD 0.99
- PolyPhen-2 0.07
- SIFT 0.24
- Most common in the African/African-American population (allele frequency 0.00041)
- Structural context available
- Literature evidence available