I66M (p.Ile66Met) variant of CD3E (P07766)
I66M (p.Ile66Met) in CD3E (P07766) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data, published literature, and structural context.
I66M (p.Ile66Met) variant details
- p.Ile66Met
- gnomAD 11-118312712-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.0825
- REVEL 0.01
- MetaLR 0.06
- MetaSVM -1.05
- CADD 3.01
- PolyPhen-2 0.01
- SIFT 0.10
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available
- Literature evidence available