I57T (p.Ile57Thr) variant of CD3E (P07766)
I57T (p.Ile57Thr) in CD3E (P07766) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, published literature, and structural context.
I57T (p.Ile57Thr) variant details
- p.Ile57Thr
- gnomAD 11-118312684-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.189
- REVEL 0.13
- MetaLR 0.14
- MetaSVM -0.93
- CADD 15.00
- PolyPhen-2 0.11
- SIFT 0.04
- Population evidence available
- Structural context available
- Literature evidence available