I46M (p.Ile46Met) variant of CD3E (P07766)
I46M (p.Ile46Met) in CD3E (P07766) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data, published literature, and structural context.
I46M (p.Ile46Met) variant details
- p.Ile46Met
- gnomAD 11-118312652-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.1
- REVEL 0.07
- MetaLR 0.09
- MetaSVM -1.02
- CADD 3.89
- PolyPhen-2 0.01
- SIFT 0.09
- Most common in the 1KG:CLM population (allele frequency 0.0053)
- Structural context available
- Literature evidence available