G68C (p.Gly68Cys) variant of CD3E (P07766)
G68C (p.Gly68Cys) in CD3E (P07766) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data, published literature, and structural context.
G68C (p.Gly68Cys) variant details
- p.Gly68Cys
- gnomAD 11-118312716-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.129
- REVEL 0.09
- MetaLR 0.22
- MetaSVM -0.92
- CADD 5.11
- PolyPhen-2 0.89
- SIFT 0.01
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00091)
- Structural context available
- Literature evidence available