E26K (p.Glu26Lys) variant of CD3E (P07766)
E26K (p.Glu26Lys) in CD3E (P07766) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
E26K (p.Glu26Lys) variant details
- p.Glu26Lys
- gnomAD rs1948119244
- Missense
- Variant Prioritization Score for Impact Estimate 0.227
- REVEL 0.13
- MetaLR 0.18
- MetaSVM -0.84
- CADD 23.80
- PolyPhen-2 0.01
- SIFT 0.19
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available