P25R (p.Pro25Arg) variant of CD3D (P04234)
P25R (p.Pro25Arg) in CD3D (P04234) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
P25R (p.Pro25Arg) variant details
- p.Pro25Arg
- TOPMed rs1591278393
- Missense
- Variant Prioritization Score for Impact Estimate 0.0838
- REVEL 0.10
- CADD 0.01
- PolyPhen-2 0.02
- SIFT 0.59
- Most common in the African/African-American population (allele frequency 0.00041)
- Structural context available