P25L (p.Pro25Leu) variant of CD3D (P04234)
P25L (p.Pro25Leu) in CD3D (P04234) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data, published literature, and structural context.
P25L (p.Pro25Leu) variant details
- p.Pro25Leu
- gnomAD 11-118340575-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.0777
- REVEL 0.09
- CADD 0.03
- PolyPhen-2 0.02
- SIFT 0.56
- Most common in the African/African-American population (allele frequency 0.00041)
- Structural context available
- Literature evidence available