L65R (p.Leu65Arg) variant of CD3D (P04234)
L65R (p.Leu65Arg) in CD3D (P04234) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
L65R (p.Leu65Arg) variant details
- p.Leu65Arg
- gnomAD rs1386584482
- Missense
- Variant Prioritization Score for Impact Estimate 0.246
- REVEL 0.21
- CADD 16.10
- PolyPhen-2 0.44
- SIFT 0.28
- Most common in the HGDP:BURUSHO population (allele frequency 0.042)
- Structural context available