L51R (p.Leu51Arg) variant of CD3D (P04234)
L51R (p.Leu51Arg) in CD3D (P04234) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data, published literature, and structural context.
L51R (p.Leu51Arg) variant details
- p.Leu51Arg
- gnomAD 11-118340497-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.168
- REVEL 0.25
- CADD 0.02
- PolyPhen-2 0.00
- SIFT 0.38
- Most common in the African/African-American population (allele frequency 0.00031)
- Structural context available
- Literature evidence available