L16F (p.Leu16Phe) variant of CD3D (P04234)
L16F (p.Leu16Phe) in CD3D (P04234) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
L16F (p.Leu16Phe) variant details
- p.Leu16Phe
- gnomAD rs1449040308
- Missense
- Variant Prioritization Score for Impact Estimate 0.288
- REVEL 0.21
- AlphaMissense 0.70
- MetaLR 0.21
- MetaSVM -0.84
- CADD 23.30
- PolyPhen-2 0.09
- Most common in the 1KG:MXL population (allele frequency 0.0081)
- Structural context available