L15I (p.Leu15Ile) variant of CD3D (P04234)
L15I (p.Leu15Ile) in CD3D (P04234) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
L15I (p.Leu15Ile) variant details
- p.Leu15Ile
- TOPMed rs892215583
- gnomAD rs892215583
- Missense
- Variant Prioritization Score for Impact Estimate 0.141
- REVEL 0.04
- AlphaMissense 0.33
- MetaLR 0.42
- MetaSVM -0.24
- CADD 0.13
- PolyPhen-2 0.90
- Most common in the 1KG:MXL population (allele frequency 0.0081)
- Structural context available