L15F (p.Leu15Phe) variant of CD3D (P04234)
L15F (p.Leu15Phe) in CD3D (P04234) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
L15F (p.Leu15Phe) variant details
- p.Leu15Phe
- TOPMed rs892215583
- gnomAD rs892215583
- Missense
- Variant Prioritization Score for Impact Estimate 0.137
- REVEL 0.02
- AlphaMissense 0.09
- MetaLR 0.44
- MetaSVM -0.11
- CADD 0.38
- PolyPhen-2 0.96
- Most common in the Middle Eastern population (allele frequency 0.0007)
- Structural context available