K23N (p.Lys23Asn) variant of CD3D (P04234)
K23N (p.Lys23Asn) in CD3D (P04234) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
K23N (p.Lys23Asn) variant details
- p.Lys23Asn
- rs370657743
- cosmic curated COSV52673
- ESP rs370657743
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.133
- REVEL 0.04
- CADD 15.50
- PolyPhen-2 0.08
- SIFT 0.10
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available