I70T (p.Ile70Thr) variant of CD3D (P04234)
I70T (p.Ile70Thr) in CD3D (P04234) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
I70T (p.Ile70Thr) variant details
- p.Ile70Thr
- ExAC rs760666412
- gnomAD rs760666412
- Missense
- Variant Prioritization Score for Impact Estimate 0.0793
- REVEL 0.07
- CADD 2.84
- PolyPhen-2 0.00
- SIFT 0.55
- Most common in the 1KG:MSL population (allele frequency 0.013)
- Structural context available