G61E (p.Gly61Glu) variant of CD3D (P04234)
G61E (p.Gly61Glu) in CD3D (P04234) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes structural context.
G61E (p.Gly61Glu) variant details
- p.Gly61Glu
- rs778408963
- NCI-TCGA Cosmic COSV5267
- cosmic curated COSV52674
- TOPMed rs778408963
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.576
- AlphaMissense 0.80
- MetaLR 0.54
- MetaSVM -0.05
- PolyPhen-2 1.00
- SIFT 0.00
- MutPred 0.77
- UniProt: Variant assessed as somatic; moderate impact.
- Structural context available