F22L (p.Phe22Leu) variant of CD3D (P04234)
F22L (p.Phe22Leu) in CD3D (P04234) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
F22L (p.Phe22Leu) variant details
- p.Phe22Leu
- 1000Genomes rs563103670
- TOPMed rs563103670
- gnomAD rs563103670
- Missense
- Variant Prioritization Score for Impact Estimate 0.0835
- REVEL 0.06
- CADD 6.79
- PolyPhen-2 0.00
- SIFT 0.70
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available