Y72H (p.Tyr72His) variant of CD28 (P10747)
Y72H (p.Tyr72His) in CD28 (P10747) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
Y72H (p.Tyr72His) variant details
- p.Tyr72His
- gnomAD rs1490784783
- Missense
- Variant Prioritization Score for Impact Estimate 0.22
- REVEL 0.18
- MetaLR 0.33
- MetaSVM -0.89
- CADD 5.29
- PolyPhen-2 0.01
- SIFT 0.51
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available