V68I (p.Val68Ile) variant of CD28 (P10747)
V68I (p.Val68Ile) in CD28 (P10747) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data, published literature, and structural context.
V68I (p.Val68Ile) variant details
- p.Val68Ile
- gnomAD 2-203726782-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.299
- REVEL 0.20
- MetaLR 0.33
- MetaSVM -0.73
- CADD 10.30
- PolyPhen-2 0.03
- SIFT 0.57
- Population evidence available
- Structural context available
- Literature evidence available