V67I (p.Val67Ile) variant of CD28 (P10747)
V67I (p.Val67Ile) in CD28 (P10747) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
V67I (p.Val67Ile) variant details
- p.Val67Ile
- TOPMed rs1332317340
- gnomAD rs1332317340
- Missense
- Variant Prioritization Score for Impact Estimate 0.149
- REVEL 0.05
- MetaLR 0.15
- MetaSVM -0.99
- CADD 10.00
- PolyPhen-2 0.21
- SIFT 0.31
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available